PRIME PubMed | CHF-PROM: validation of a patient-reported outcome measure for patients with chronic heart failure (2024)

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PRIME PubMed | CHF-PROM: validation of a patient-reported outcome measure for patients with chronic heart failure (1)

Abstract

BACKGROUND

Due to a lack of an appropriate disease-specific patient-reported outcome (PRO) instrument for chronic heart failure including its social support and treatment aspects in China, this study was performed to develop a patient-reported outcome measure (PROM) for patients with chronic heart failure and evaluate its reliability, validity, and feasibility.

METHODS

According to the standard PROM guidelines established by the Food and Drug Administration, an item pool was formed by reviewing a large amount of relevant literature and interviewing patients with chronic heart failure about their main symptoms. Thus, the primary scale was created after adjusting the items and language with the help of patients and experts in the field. Next, 155 patients from 8 hospitals in different districts were recruited for a pilot survey using questionnaires containing these items. The patients' responses were analyzed using the classical test theory and item response theory to select high-quality items and determine the subdomains of the scale. This was followed by a formal investigation in the same eight hospitals. In total, 360 patients and 100 healthy subjects were included to evaluate the reliability, validity, and feasibility of the items. Through this process, the final scale was established.

RESULTS

The final scale comprised 12 subdomains with 57 items related to physical, psychological, social, and therapeutic areas. The data analysis results of the formal investigation showed that the PROM for chronic heart failure had good reliability, validity, and feasibility. Reliability was verified by Cronbach's alpha coefficient, which was 0.913 for the total scale, 0.903 for the physical domain, 0.941 for the psychological domain, 0.827 for the social domain, and 0.839 for the therapeutic domain. The construct validity results met the relative criteria of confirmatory factor analysis. Discriminant validity was represented by score comparisons of nine subdomains. The response rate and the effective rate of return of the CHF-PROM were 98.94% and 98.92%, respectively.

CONCLUSIONS

The final scale coincides with the theoretical framework and better reflects the overall quality of life of patients with chronic heart failure. This scale can be used as a valid instrument to evaluate clinical treatment and clinical trials of chronic heart failure.

Authors+Show Affiliations

Tian J

Department of Cardiology, The 1st Hospital of Shanxi Medical University, 85 South Jiefang Road, Taiyuan, Shanxi Province, 030001, China.

Xue J

Department of Health Statistics, School of Public Health, Shanxi Medical University, 56 South XinJian Road, Taiyuan, Shanxi Province, 030001, China.

Hu X

Department of Health Statistics, School of Public Health, Shanxi Medical University, 56 South XinJian Road, Taiyuan, Shanxi Province, 030001, China.

Han Q

Department of Cardiology, The 1st Hospital of Shanxi Medical University, 85 South Jiefang Road, Taiyuan, Shanxi Province, 030001, China. syyyqhhan@sohu.com.

Zhang Y

Department of Health Statistics, School of Public Health, Shanxi Medical University, 56 South XinJian Road, Taiyuan, Shanxi Province, 030001, China. sxmuzyb@126.com. Shanxi Medical University molecular imaging precision medicine Collaborative Innovation Center, Taiyuan, Shanxi Province, 030001, China. sxmuzyb@126.com.

MeSH

AdultCase-Control StudiesChinaChronic DiseaseFactor Analysis, StatisticalFemaleHeart FailureHumansMaleMiddle AgedPatient Reported Outcome MeasuresQuality of LifeReproducibility of Results

Pub Type(s)

Journal Article

Multicenter Study

Validation Study

Language

eng

PubMed ID

29554963

Citation

Tian, Jing, et al. "CHF-PROM: Validation of a Patient-reported Outcome Measure for Patients With Chronic Heart Failure." Health and Quality of Life Outcomes, vol. 16, no. 1, 2018, p. 51.

Tian J, Xue J, Hu X, et al. CHF-PROM: validation of a patient-reported outcome measure for patients with chronic heart failure. Health Qual Life Outcomes. 2018;16(1):51.

Tian, J., Xue, J., Hu, X., Han, Q., & Zhang, Y. (2018). CHF-PROM: validation of a patient-reported outcome measure for patients with chronic heart failure. Health and Quality of Life Outcomes, 16(1), 51. https://doi.org/10.1186/s12955-018-0874-2

Tian J, et al. CHF-PROM: Validation of a Patient-reported Outcome Measure for Patients With Chronic Heart Failure. Health Qual Life Outcomes. 2018 Mar 20;16(1):51. PubMed PMID: 29554963.

* Article titles in AMA citation format should be in sentence-case

TY - JOURT1 - CHF-PROM: validation of a patient-reported outcome measure for patients with chronic heart failure.AU - Tian,Jing,AU - Xue,Jiangping,AU - Hu,Xiaojuan,AU - Han,Qinghua,AU - Zhang,Yanbo,Y1 - 2018/03/20/PY - 2017/08/22/receivedPY - 2018/02/27/acceptedPY - 2018/3/21/entrezPY - 2018/3/21/pubmedPY - 2018/7/27/medlineKW - Chronic heart failure (CHF)KW - Item response theory (IRT)KW - Item selectionKW - Patient-reported outcome (PRO)KW - ReliabilityKW - ValiditySP - 51EP - 51JF - Health and quality of life outcomesJO - Health Qual Life OutcomesVL - 16IS - 1N2 - BACKGROUND: Due to a lack of an appropriate disease-specific patient-reported outcome (PRO) instrument for chronic heart failure including its social support and treatment aspects in China, this study was performed to develop a patient-reported outcome measure (PROM) for patients with chronic heart failure and evaluate its reliability, validity, and feasibility. METHODS: According to the standard PROM guidelines established by the Food and Drug Administration, an item pool was formed by reviewing a large amount of relevant literature and interviewing patients with chronic heart failure about their main symptoms. Thus, the primary scale was created after adjusting the items and language with the help of patients and experts in the field. Next, 155 patients from 8 hospitals in different districts were recruited for a pilot survey using questionnaires containing these items. The patients' responses were analyzed using the classical test theory and item response theory to select high-quality items and determine the subdomains of the scale. This was followed by a formal investigation in the same eight hospitals. In total, 360 patients and 100 healthy subjects were included to evaluate the reliability, validity, and feasibility of the items. Through this process, the final scale was established. RESULTS: The final scale comprised 12 subdomains with 57 items related to physical, psychological, social, and therapeutic areas. The data analysis results of the formal investigation showed that the PROM for chronic heart failure had good reliability, validity, and feasibility. Reliability was verified by Cronbach's alpha coefficient, which was 0.913 for the total scale, 0.903 for the physical domain, 0.941 for the psychological domain, 0.827 for the social domain, and 0.839 for the therapeutic domain. The construct validity results met the relative criteria of confirmatory factor analysis. Discriminant validity was represented by score comparisons of nine subdomains. The response rate and the effective rate of return of the CHF-PROM were 98.94% and 98.92%, respectively. CONCLUSIONS: The final scale coincides with the theoretical framework and better reflects the overall quality of life of patients with chronic heart failure. This scale can be used as a valid instrument to evaluate clinical treatment and clinical trials of chronic heart failure. SN - 1477-7525UR - https://www.unboundmedicine.com/medline/citation/29554963/CHF_PROM:_validation_of_a_patient_reported_outcome_measure_for_patients_with_chronic_heart_failure_DB - PRIMEDP - Unbound MedicineER -

PRIME PubMed | CHF-PROM: validation of a patient-reported outcome measure for patients with chronic heart failure (2024)

FAQs

What are the outcome measures for heart failure? ›

Outcome measures

With respect to patients with heart failure, widely used outcomes measures include mortality and readmission following hospitalization. These outcomes are appealing on a clinical and policy level because they occur relatively frequently in patients who have been hospitalized with heart failure.

What is the prognosis for heart failure in the UK? ›

A UK population-based cohort (55,959 patients) study between 2000 and 2017 found that 30,906 patients died during that period and heart failure was listed as the primary cause of death in 7.2% [Taylor, 2019]. In this study — 1, 5, and 10 year survival rates were 80.8%, 48.2%, and 26.2%.

What is the prognosis for congestive heart failure? ›

One study says that people with congestive heart failure have a life span 10 years shorter than those who don't have heart failure. Another study showed that the survival rates of people with chronic heart failure were: 80% to 90% for one year. 50% to 60% for year five.

What are the desired outcomes of CHF? ›

Expected outcomes:

Patient will display hemodynamic stability with vital signs, cardiac output, and renal perfusion within normal limits. Patient will participate in activities that reduce the workload of the heart. Patient will report an absence of chest pain or shortness of breath.

What are the expected outcomes for a client with heart failure? ›

Goals and expected outcomes may also include: The patient will exhibit optimal cardiac output, indicated by vital signs within acceptable ranges, absence/control of dysrhythmias, and absence of heart failure symptoms. The patient will engage in activities that reduce cardiac workload.

What is the prognostic index of heart failure? ›

The index is calculated using the following formula: 220 - age - heart rate + systolic blood pressure - (creatinine ×10).

What is heart failure in pubmed? ›

Abstract. Heart failure is a clinical syndrome that results when the heart is unable to provide sufficient blood flow to meet metabolic requirements or accommodate systemic venous return.

What factors determine the prognosis of heart failure? ›

Many factors can affect a person's life expectancy with congestive heart failure (CHF), such as their age, the stage of their condition, and the strength of their heart function. CHF is a chronic, progressive condition that affects the heart's ability to pump blood around the body.

What is the longest you can live with CHF? ›

While no one can predict exactly how heart failure will affect someone's life or how it may shorten a life, in general, more than half of all people diagnosed with congestive heart failure will survive for five years. About 35% will survive for 10 years.

What does stage 4 congestive heart failure look like? ›

Stage 4 heart failure is the most severe, and you will be showing symptoms regardless of what activity you are doing. You may feel issues like shortness of breath, nausea, light-headedness, chest pain, and swelling even when you are completely at rest. Generally speaking, stage 4 heart failure is treated in hospital.

What's the best thing to drink with congestive heart failure? ›

Water is the drink of choice for heart health. If you're thirsty, drink water.

How quickly does heart failure progress? ›

Heart failure is a chronic condition that worsens overtime without the proper treatment and management. Symptoms of heart failure can progress anywhere from a few months to decades.

What not to do with heart failure? ›

It's important to avoid exercise that involves heavy weight-lifting, or holding your breath. Don't do any exercises that use your whole body as a weight, such as press-ups or planks. And be careful if you're getting in the pool.

What are the core measures for heart failure? ›

Currently, core measures for HF include: use of an angiotensin-converting enzyme inhibitor (ACEI) or an angiotensin II receptor blocker (ARB) for left ventricular systolic dysfunction (LVSD) left ventricular function (LVF) assessment. smoking cessation counseling.

What is the measurement for heart failure? ›

Ejection fraction measures how well your heart pumps. This helps diagnose the type of heart failure you have and guides your treatment. If 40% or less of the blood in your left ventricle is pumped out in one beat, you have heart failure with reduced ejection fraction.

What is the most important assessment for heart failure? ›

Ejection fraction.

Ejection fraction is a measurement of the percentage of blood leaving your heart each time it squeezes. This measurement is taken during an echocardiogram. The result helps classify heart failure and guides treatment. An ejection fraction of 50% or higher is considered ideal.

What are the goals for heart failure patients? ›

Left untreated, heart failure is generally a progressive condition. The goal of treatments for heart failure is to relieve symptoms; reduce the chances that you will develop complications; and slow, stop, or reverse the progression of the underlying process.

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